What to Expect During and After NAD IV Therapy | Biofuse

What to Expect During and After Your First NAD IV Therapy Session

NAD IV Therapy is quickly becoming one of the most sought-after treatments in wellness clinics across the country. Whether you're looking for more energy, improved focus, or long-term support for healthy aging, this therapy is known for delivering results.

That’s because NAD+, a coenzyme found in every cell of the body, is essential for energy production, cognitive function, and cellular repair. However, research from the National Institutes of Health shows that NAD+ levels decline naturally with age leading to symptoms like fatigue, brain fog, and slower metabolism. NAD IV Therapy helps replenish these levels by delivering NAD+ directly into the bloodstream for immediate absorption and rapid results.

If you're curious about what the experience is like, this guide will walk you through exactly what to expect before, during, and after your NAD IV therapy session, and how it may leave you feeling afterward.

What Is NAD IV Therapy and How Does It Work?

Nicotinamide Adenine Dinucleotide (NAD+) plays a vital role in converting nutrients into energy, repairing damaged cells, and supporting brain health. Delivering NAD+ through an IV bypasses the digestive system, allowing your body to absorb it at close to 100% efficiency far more effectively than oral supplements.

For a deeper breakdown of this essential coenzyme, see our post on what NAD IV therapy is.

Before Your First NAD IV Therapy Session

Consultation and Health Review

Your experience begins with a quick online intake form where you’ll share your health history, symptoms, and goals. Our licensed professionals review this ahead of time to ensure NAD IV therapy is safe and aligned with your wellness needs.

Choosing the Right Drip

Based on your profile, we tailor the dose and type of NAD+ therapy to fit your goals—whether you're boosting energy, improving focus, or supporting recovery. If you’re new to NAD, this is a great first step toward a more personalized health plan. For deeper insight into frequency, check out our guide on how often you can get NAD IV therapy.

Preparing for Your Session

To get the most out of your treatment:

  • Stay well-hydrated

  • Eat a light meal beforehand

  • Avoid alcohol and strenuous exercise right before your visit

What Happens During the Session

Arrival and Check-In

When you arrive, our team will confirm your intake has been completed and proceed with your appointment. There’s no need to re-fill forms onsite—your care starts right away.

Setup and Infusion

A registered nurse will help you settle into a comfortable seat. They’ll place an IV catheter into your arm and begin your customized NAD drip. The infusion is carefully monitored to ensure you remain relaxed and supported throughout.

Session Duration

Most NAD IV sessions last 30 minutes to 1 hour, depending on the dosage and your treatment plan. Some clients may need more time during their initial session, especially when starting at lower drip rates to reduce sensitivity.

How You Might Feel During NAD IV Therapy


Once you’re comfortably seated, a registered nurse will gently place a small IV in your arm and begin your NAD+ infusion at a carefully controlled, gradual pace.

Because NAD+ works at the cellular level to boost energy production, it’s completely normal to experience some sensations as your body adjusts. You may feel mild chest tightness, abdominal pressure, lightheadedness, or an overall “heavy” feeling during the infusion — especially early on. These feelings are temporary and simply a sign that your mitochondria (the energy centers of your cells) are being activated.

By starting your infusion slowly, we help minimize these sensations and give your body time to adapt comfortably. Throughout your session, your nurse will monitor you closely and adjust the drip rate if needed to keep you feeling as relaxed and supported as possible.

How You Might Feel After NAD IV Therapy

Everyone responds differently, but most clients report feeling:

  • Refreshed and clear-headed

  • Mentally sharper with reduced brain fog

  • More energized throughout the day or the following morning

  • Calmer and balanced, emotionally and physically

Some individuals may feel slightly fatigued after their first treatment—this is normal and usually fades quickly. As your body adjusts and NAD+ levels normalize, sessions often leave you feeling noticeably uplifted.

Real Feedback from Biofuse Clients

“My brain fog was gone within hours. I felt recharged and had more focus at work the next day.”
— Amanda, Boise

“I didn’t expect it to be so calming. I walked out of my first NAD IV session feeling like I had just reset everything.”
— Josh, Traverse City

Where to Get NAD IV Therapy Near You

You can receive safe, medically supervised NAD IV therapy at any of our convenient Biofuse locations:

NAD IV Therapy in Grand Rapids, Michigan
Biofuse | NAD IV Therapy
465 Fuller Ave NE Suite C, Grand Rapids, MI 49503
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NAD IV Therapy in Traverse City, Michigan
Biofuse | NAD IV Therapy
540 S Garfield Ave, Traverse City, MI 49686
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NAD IV Therapy in Portage, Michigan
Biofuse | NAD IV Therapy
7097 S Westnedge Ave, Portage, MI 49002
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NAD IV Therapy in Boise, Idaho
Biofuse | NAD IV Therapy
7610 W State St #125, Boise, ID 83714
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Ready to Try NAD IV Therapy?

Now that you know what to expect, your first NAD IV session can be the beginning of a personalized wellness journey. Biofuse offers professional, medically guided care in a relaxing environment—designed to help you feel your best, inside and out.

Book Your NAD IV Therapy Appointment Today

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